Molecular Mechanisms of Neurodegenerative Diseases by Marie-Francoise Chesselet

Molecular Mechanisms of Neurodegenerative Diseases



Download Molecular Mechanisms of Neurodegenerative Diseases




Molecular Mechanisms of Neurodegenerative Diseases Marie-Francoise Chesselet
Language: English
Page: 410
Format: pdf
ISBN: 0896038042, 9780896038042
Publisher: Humana Press

Marie-Françoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from different yet complementary points of view. Focusing on Alzheimer's, Parkinson's, and CAG triplet repeat diseases, the authors show how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and may lead to new therapeutics. Topics include the role of Ab toxicity, glial cells, and inflammation in Alzheimer's disease; the formation of abnormal protein fragments across several diseases, the impact of dopamine and mitochondrial dysfunction on neurodegeneration. Authoritative and insightful, Molecular Mechanisms of Neurodegenerative Diseases synthesizes the novel ideas and concepts now emerging to create a fresh understanding of neurodegenerative disorders, one that promises to lead to powerful new therapies that prevent, delay the onset, slow the progression, or even cure these cruel diseases.

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